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A wide variety of infertility treatments for both sex

Causes of Infertility

Infertility is a condition that is experienced by one out of ten couples. Infertility occurs when the couple cannot have a child despite the regular sexual intercourse for a period of one year without using any birth control methods.

Infertility may be observed with both men and women. Therefore, both spouses should be examined and have diagnostic tests performed during the diagnosis and treatment of infertility.

Causes of Male Infertility

  • Low sperm count
  • Poor sperm motility, sperm cannot pass through the uterus to reach the egg.
  • Sperm cannot penetrate the exterior of the egg due to its “morphology” (distorted shape)
  • Lack of sperm production or sperm completely (may be due obstruction in sperm tracts).

These disorders may result from the following:

  • Varicocele (enlargement of testicular vessels )
  • Testicular infections (mumps, etc.).
  • Hormonal disorders
  • Testicular tumors
  • Genetic abnormalities
  • Immunological causes (presence of agents called antibody and produced against sperm and eliminates them)
  • Psychological causes
  • Difficulties in sexual intercourse, erection or ejaculation problems.

Causes of Female Infertility

  • Hormonal disorders
  • Blocked or damaged tubes
  • Uterus-related structural problems
  • Endometriosis
  • Immunological causes
  • Genetic disorders
  • Psychological causes
Tests used as a basis for diagnosis;
  • Hormone analysis contains Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), which indicate ovarian functions, Anti-Mülleryen Hormone (AMH), which indicates ovarian capacity, Testosterone and DHEA-S, which are male hormones, and Prolactin, normally responsible for milk production.
  • Ultrasound is performed to view size, shape and status of the ovaries and uterus, i.e.,, female internal genital organs. In addition, the number of eggs with a possibility to develop in the ovaries in that month can be determined.
  • Semen analysis is a test that is applied to men to measure the quality of male reproductive cells.
    • Normal values ​​are as follows:
    • Minimum 15 million / ml
    • Motility: A total of 40 million / ml forward in minimum
    • Morphology “shape”: Minimum 4%

In addition to these tests, Laparoscopy, Hysteroscopy, Hysterosalpingography and genetic tests are also available.

great care in every step of this miraculous journey of building a family.

What is IVF?

IVF (In Vitro Fertilisation) is a procedure, applied to eliminate a variety of fertility problems. The method basically involves putting the egg and the sperm together outside the body, in a specialized laboratory environment. And allocating a period of time for the embryo to grow in a special, preserved environment before it is transferred into the woman’s uterus. IVF can be considered one of the most successful methods for couples who are willing to have a baby.

Why IVF?
IVF can be the option for the couples who are suffering from some of the mentioned problems below;
A range of fertility issues,
– IVF failures you have experienced earlier.
– Age is one of the most crucial issues affects the possibility of having a baby for couples who are willing to build a family.
For the women, earlier ages, especially earlier than the age 30, are the most available times to have a baby. As a woman get older, the chance of having a baby decreases.
For the men, this average is increasing till the age of 41 in men. For the couples who are having IVF treatment, if the man is younger than 41, the chance of having a baby getting higher.
– A genetic disorder; If there is any risk of passing on a genetic disorder to your child due to a problem related with you or your partner, you may benefit from IVF to eliminate this risk by preimplantation genetic diagnosis.
– Preservation of fertility for cancer or any other diseases may harm fertility; some of the treatment methods decrease your fertility rate such as radiation or chemotherapy, so IVF is one of the options for the preservation.
-If the sperm concentration is down under the average and the mobility rate of sperms is low or if there are some abnormal issues in sperm size and the shape, these may cause some difficulties for a sperm to fertilize an egg. In such mentioned cases, IVF may be an option for men.
-Although the necessary tests and evaluations have been made and no problem diagnosed, IVF can be one of the treatment methods for the people who cannot have a baby due to unexplained infertility problem.
– If a woman loses the normal ovarian function before the age 40, this is called ”premature ovarian failure”; it can be one of the reasons that you may decide to get the IVF treatment.

If you are planning to become a parent in near future, this will be the perfect time to get detailed information regarding your reproductive health. This early notice regarding your fertility will provide you with more options when you finally give your decision to go after parenthood.
What is a Fertility Awareness Checkup?
A Fertility Awareness Checkup is an early examination in order to provide a primary overview of your reproductive potential thus to help you with prior knowledge in your future parenting plans.
What are the benefits of Fertility Awareness Checkup?
– Makes you relieve your stress
– Help you save valuable time
– Help you save money
This will help alleviate stress, as well as save valuable time and financial resources in your journey to become a parent. This checkup involves the most predictive fertility testing up to date to demonstrate your potential for getting pregnant.
For women, fertility awareness checkup contains
– Blood tests ;
Day 3 FSH (Follicle Stimulating Hormone)
Day 3 Estradiol
– The Basal Antral Follicle Count test is done to measure a woman’s ovarian reserve or remaining egg supply through the transvaginal ultrasound. Fertility potential is indicated by the results of ovarian reserves.
For men, fertility awareness checkup contains
– Semen analysis

Who Should Get Tested?
American Society for Reproductive Medicine explains that approximately one-third of infertility is attributed to the female partner, one-third attributed to the male partner and one-third is caused by a combination of problems in both partners or, is unexplained. If you are planning to be a parent, regardless of your sex, regardless of being a couple or an individual, everyone needs to get the fertility awareness check. In addition to the challenges following the IVF decision, there are advantages and opportunities of IVF provides; here you will find a list includes both parts:

1. IVF can be time-consuming.
2. There can be some stressful times in the IVF process.
3. Contrary to general belief, being stressful is not making harder to get pregnant
4- You may feel moody due to the flow of hormones.
5- Fertility treatments you are getting while the IVF process may increase the tendency of depression and anxiety, including postpartum depression.
6-IVF injections may cause some mild effects which make you feel uncomfortable at times.
7. The IVF process may affect your relationship with your partner.
8- It generally takes more than one cycle of IVF to achieve the state of pregnancy
9- IVF gives the chance of choosing your baby’s gender by the help of an additional screening process.
10. IVF can be considered the most effective way for infertile couples to have a baby, thus it is better to choose the IVF (in vitro fertilization (IVF)) method compared to various assisted reproductive Technologies and better to be consistent at every stage of this treatment.
11- All through this period, the most crucial thing is your self-awareness and keeping yourself in a healthy and good condition.

We have some suggestions for you ;
Before deciding to get the IVF treatment, patients need to understand the total treatment processes and all the steps involved in this treatment. This is the best way to eliminate any bias and concerns and to be prepared for the emotional and physical changes that this treatment may cause.
Adequate and balanced nutrition and attending a regular physical exercise program are the most advantageous actions you may take to obtain successful results from IVF treatment and give a good start to any fertility journey. Scientific researches indicate that the chances of success in IVF rise up when the women are physically and emotionally in a good condition.
Especially in women, it is essential for choosing the most appropriate time period for IVF treatment. This appropriateness can be described as being away from high-stress and the major changes in life at this period, such as a career shift, moving abroad etc.
A solid support system needs to build and strengthen when you are undergoing IVF. This support group involves family, friends and some patient groups or online forums. Especially at this period, when patients’ moods are significantly affected by the fertility drugs, existence and the continuity of the support of these people will relieve your stress, make you feel safe and surrounded by your beloved ones. Besides these, sharing your concerns with a group of people who have been experienced similar stages of IVF procedure will make you feel comfortable and less anxious about the treatment.
Blocking out the negative opinions is in favor of you and your partner in the IVF period. However, it should not be forgotten the requirement of being realistic and mindful about the factors such as age, weight, habits and the general state of health. These are the most important factors determine the possibility of success of IVF. 

Human Reproduction and Development of Germ Cells

Female germ cell (egg = oocyte) and male germ cell (sperm), the keystones of human reproduction, pass through many development phases until they gain the potential to create a new organism. The ovaries in female and the testicles in male act as a repository to germ cells during their development and fully mature human germ cells throughout their life cycle.

While the ovaries and the testicles act as a repository for germ cells, they also allow these cells to continue to live by releasing a variety of hormones on the other hand. Testosterone in male and estrogen in female are the most important hormones released for this purpose. The release of these hormones is controlled by some centers in the brain.

Egg production in female begins in the mother’s womb. A new-born female child has 2 to 3 million eggs. This number decreases by 400 thousand in adolescence. Eggs are stored in the ovaries in balloon-like structures that we call follicle.

Eggs remain at rest during a certain period of their development until adolescence. With the beginning of adolescence, the release of hormones in the body gains a rhythm. As a result, the brain ensures release of GnRH (gonadotropin releasing hormone), released from a special region of the brain called hypothalamus, FSH (follicle stimulating hormone) from the pituitary gland located in the brain and LH (Luteinizing hormone).

Follicle-stimulating hormone, as the name suggests, stimulates the follicles in the ovaries with germ cells. As a result, egg reaches a maturity by continuing its development so that it can be fertilized by sperm. FSH provides the release of estrogen hormone by stimulating also the follicle cells surrounding the egg. This hormone is essential for the development of eggs. The diameter of the follicle, which is 1 to 2 mm in diameter at rest, reaches 20 to 25 mm with the effect of the FSH hormone. The follicle that reaches this size hatches and becomes free. This is called ovulation. Ovulation in a female with a regular menstruation cycle, i.e., having a period in every 28 to 30 days, coincides with the 14th to 15th days of the menstruation cycle, in other words, with the middle of the cycle.

Immediately after the menstrual period, 5 to 10 follicles in the ovary begin to grow with the effect of FSH, but only one of them grows enough and then hatches. In short, normally only one egg in each month is ready for fertilization. The number of follicles in the ovaries decreases closer to menopause, the period with zero remaining follicle is called menopause.

Unlike women, production of sperm in men begins with adolescence. FSH and LH hormones are also released in men like in women. These hormones allows production and maturation of sperm cells by affecting the testicles. Testosterone hormone, released by the testicles with the effect of FSH and LH, is the basic hormone that allows production and maturation of sperm cells.


The egg laid with the ovulation is taken into the tube through contraction of the tubes and movements of the region adjacent to the ovaries. After sexual intercourse, sperm cells pass through the uterus from vagina and then to the tubes. Fertilization which means the fusion of egg and sperm with each other) takes place in the tubes. Human sperm and egg are capable of remaining alive up to about 24 hours until fertilization in the female reproductive tracts. The fertilized egg arrives in the uterus cavity in a period of 3 to 4 days with rhythmic contractions of the tubes. The number of cells in the egg fertilized in this 3-4 day period increases with division, and the embryo (fertilized egg cell) will have approximately 16 cells when arrived in the intra-uterine cavity. Blastocyst is a further developed embryo and is ready for implantation in the intra-uterine cavity.


Implantation refers to the placement and bedding of the embryo in the uterine cavity. The mucosal tissue lining the inside of the uterus (endometrium) must be ready for implantation for a healthy implantation. The embryo placing in the intra-uterine cavity soundly will create the fetus in the future by continuing its development.


Duration: Flexible
Tour starting point: Hotel
Tour ending point: Hotel
Includes: Private tour, pick-up from hotel
Excludes: Transportation, gratitudes (recommended)


  • Enjoy the personalized experience of a private medical tour
  • Customize the itinerary to your interests
  • Light refreshments


  • Transportation
  • Museum Entrance Tickets
  • Gratitude (suggested)


Q: Can I choose the sights to visit on my own?
A: Sure! You can choose the sights and museums along all sort of criteria you like in accordance with your tour guide.

Q: How to buy museum tickets?
A: No need to buy tickets in advance, during the tour your tour guide will help you to purchase them.

Q: How to meet my tour guide?
A: Your tour guide will be waiting in your hotel to meet you at a determined time.

Q: Can I state the departure time for my tour?
A: Of course! We operate tours on private basis, so you can customize the departure time.

Q: Am I traveling with a group on the tour?
A: No, we provide private tours for your best experience so you will have a private professional tour guide in your preferred language.

Q: How about the transportation?
A: When you book your tour with a van, you will be picked up from hotel, be transferred to the sights and then back to hotel. Otherwise, once you meet your tour guide at your hotel, you will be advised the best option for transportation such as taxi, metro or tram.

Q: How about shopping in Istanbul?
A: If you have any interest in workshops, please indicate while booking.

Q: How do I book this private Istanbul tour?
A: Easy! All you need to do is;
Fill the ‘Booking’ form where you will put your full details such as personal information, date, hotel or cruise name, arrival and departure times. Once you complete your booking we will get back to you with a confirmation email within 24 hours.

Q: How do I pay?
A: After filling the Booking form and secure the booking, the payment will be in cash directly to the tour guide during the tour. You can choose to pay in Usd, Euro, RMB, Turkish Lira or English Sterling.

Cancellation Policy

Note to our beloved guests:
To receive a full refund;
Please try to cancel at least 72 hours in advance of the start date of the experience.
For details please refer to our Cancellation & Refund Policy.
Thank you!

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